منابع مشابه
Impaired cutaneous wound healing in interleukin-6-deficient and immunosuppressed mice.
It has been postulated that an inflammatory response after cutaneous wounding is a prerequisite for healing, and inflammatory cytokines, such as interleukin-6 (IL-6), might be intimately involved in this process. IL-6-deficient transgenic mice (IL-6 KO) displayed significantly delayed cutaneous wound healing compared with wild-type control animals, requiring up to threefold longer to heal. This...
متن کاملPotential implications of interleukin-7 in chronic wound healing
Methods of identifying chronic wounds that will heal in a timely, coordinated fashion and those that will not, together with novel therapeutic strategies, are vital for progression in the field of wound healing. Interleukin (IL)-7 has been associated with various biological and pathological processes. The present study explored the potential role of IL-7 in wound healing. IL-7 expression levels...
متن کاملBiology and Biomarkers for Wound Healing WOUND HEALING
www.PRSJournal.com 18S Wound healing is a multifaceted process governed by sequential yet overlapping phases, including hemostasis, inflammation, proliferation, and remodeling. This process is executed through communication between the various local skin compartments, supporting extracellular matrix, and systemic contributors. Under physiological conditions in a healthy individual, the process ...
متن کاملOxygen and Wound Healing
Oxygen is essential to several critical mechanisms in wound healing, including bacterial killing, angiogenesis, fibroplasia, and epithelialization. As a substrate, oxygen provides the respiratory burst necessary for white blood cells to kill engulfed bacteria, hastening resolution of inflammation so that a preliminary matrix can be formed for subsequent fibroplasia and epithelialization. Additi...
متن کاملPlatelets and wound healing.
Platelets help prevent blood loss at sites of vascular injury. To do this, they adhere, aggregate and form a procoagulant surface favoring thrombin generation and fibrin formation. In addition, platelets express and release substances that promote tissue repair and influence processes such as angiogenesis, inflammation and the immune response. They contain large secretable pools of biologically...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1994
ISSN: 0007-0912
DOI: 10.1093/bja/73.3.426